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Original Article
9 (
1
); 9-14

Study of alterations in Lipid profile after Burn injury.

Associate Professor, Department of Biochemistry, B. J. Medical College, Ahmedabad.
Professor, Department of Burns & Plastic Surgery, Civil Hospital, Ahmedabad.
Resident Doctor, Department of Biochemistry, B. J. Medical College, Ahmedabad.

*Corresponding Author: Dr. Asha Khubchandani E-mail: ashakhub@yahoo.com

Licence
This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial-Share Alike 4.0 License, which allows others to remix, transform, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms.

Abstract

Introduction:

After burn injury, changes in lipid profile occur in body. Dyslipidemia after burn injury is one of the important alterations.

Objective:

To check alterations in lipid profile after burn injury.

Materials and Method:

It was cross sectional study which was carried out on 250 burns patients of both sex, with an age group of 18-45 years, and varying burns percentage of 20-80% of total body surface area (TBSA). Serum cholesterol, serum LDL, serum HDL and serum triglyceride level were measured on XL-640 fully-auto biochemical analyser. Serum LDL and HDL were measured by Accelerator Selective Detergent Method. Serum cholesterol and triglyceride were measured by Trindor’s method.

Results:

Results showed decrease in serum cholesterol, serum LDL and serum HDL, while increase in serum triglyceride level in burns patients compared to normal subjects.

Conclusion:

This study clearly showed the importance of measuring serum cholesterol, TG, LDL and HDL in burn patients and targeting changes that occur in their levels along the burns course, which may have beneficial effect in protection from organ damage, increasing survival rates and improving burn outcome.

Keywords

Triglyceride (TG)
Low-density lipoprotein (LDL)
High-density lipoprotein (HDL)

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