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Original Article
15 (
1
); 16-21
doi:
10.56018/2023063

Reticulocyte Hemoglobin Content (CHr): A Reliable indicator in Iron Deficiency Anemia

Third Year Resident, Department of Pathology, BJ Medical College, Ahmedabad
Assistant Professor, Department of Pathology, BJ Medical College, Ahmedabad
Head of Department, Department of Pathology, BJ Medical College, Ahmedabad

*Corresponding author: Dr. Parikh UR Email: urviparikh76@gmail.com

Licence
This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial-Share Alike 4.0 License, which allows others to remix, transform, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms.

Abstract

Introduction:

To estimate a cut off for Reticulocyte Hemoglobin Content (CHr) and compare it with Serum Ferritin for diagnosis of Iron Deficiency Anemia (IDA).

Material & Methods:

A total of 188 samples were included in the analytical study out of which 126 were categorized as study samples and 62 as control. CBC and Reticulocyte analysis were carried out and the parameters were compared.

Results:

CHr has a better sensitivity and specificity compared to Serum Ferritin. Low CHr is a marker for early diagnosis of iron deficiency whereas a raised CHr is an early sign of response to iron therapy. A CHr cut-off of 28.4 pg was established which is comparable with that of other studies.

Conclusion:

The study demonstrates that CHr is a useful parameter that can be confidently used in the diagnosis of IDA.

Keywords

Reticulocyte Hemoglobin Content (CHr)
Iron Deficiency Anemia (IDA)
ROC curve

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